Christian Grimm Selected Research

Peptide Hydrolases (Proteases)

10/2020

Extended interaction networks with HCV protease NS3-4A substrates explain the lack of adaptive capability against protease inhibitors.

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Christian Grimm Research Topics

Disease

26	Retinal Degeneration 12/2022 - 03/2002
20	Hypoxia (Hypoxemia) 03/2022 - 07/2002
13	Neoplasms (Cancer) 12/2023 - 07/2008
10	Macular Degeneration (Age-Related Maculopathy) 01/2023 - 09/2012
6	Retinal Diseases 01/2023 - 06/2000
5	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2023 - 10/2008
5	Mucolipidoses (Sialidosis) 01/2021 - 11/2009
5	Inflammation (Inflammations) 01/2020 - 01/2017
4	Infections 01/2023 - 02/2015
4	Atrophy 01/2023 - 04/2009
4	Edema (Dropsy) 10/2020 - 04/2008
3	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2023 - 09/2012
3	Ischemia 10/2020 - 01/2006
3	Gliosis 10/2019 - 04/2008
3	Optic Neuritis (Retrobulbar Neuritis) 10/2019 - 01/2018
2	Stargardt Disease 10/2023 - 01/2023
2	Eye Diseases (Eye Disease) 01/2023 - 10/2016
2	Color Vision Defects (Color Blindness) 01/2023 - 07/2022
2	Emphysema 01/2022 - 01/2022
2	Melanoma (Melanoma, Malignant) 01/2021 - 01/2021
2	Obesity 01/2021 - 01/2017
2	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 07/2008
2	Disease Progression 11/2019 - 09/2012
2	Retrograde Degeneration 10/2019 - 01/2019
2	Neoplasm Metastasis (Metastasis) 01/2018 - 01/2017
2	Glaucoma 08/2015 - 09/2012
2	Angle-Closure Glaucoma (Glaucoma, Angle Closure) 08/2015 - 01/2008
2	Retinopathy of Prematurity (Retrolental Fibroplasia) 09/2012 - 09/2005
2	Hypertrophy 08/2008 - 04/2008
2	Hearing Loss (Hearing Impairment) 12/2007 - 06/2007
1	Bacterial Infections (Bacterial Infection) 01/2023
1	Epidemic Louse-Borne Typhus (Typhus) 01/2023
1	Retinal Detachment (Retinal Detachments) 01/2023
1	Choroideremia 01/2023
1	Plague (Bubonic Plague) 01/2023
1	Communicable Diseases (Infectious Diseases) 01/2023
1	Cholera 01/2023
1	Starvation 01/2023
1	Parkinson Disease (Parkinson's Disease) 12/2022
1	Iron Overload 12/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 07/2022
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2022
1	Leukemia 01/2022
1	Lung Diseases (Lung Disease) 01/2022
1	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 01/2022
1	Lung Injury 01/2022
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2022

Drug/Important Bio-Agent (IBA)

33	Retinaldehyde (Retinal)IBA 01/2023 - 06/2000
13	Transcription Factors (Transcription Factor)IBA 01/2022 - 01/2006
12	CationsIBA 01/2023 - 01/2017
12	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2006
6	Oxygen (Dioxygen)IBA 01/2023 - 01/2011
6	Two-Pore ChannelsIBA 01/2022 - 08/2014
4	LipidsIBA 01/2023 - 01/2018
4	Bacterial ToxinsIBA 01/2021 - 01/2017
4	Ion Channels (Ion Channel)IBA 01/2021 - 12/2007
4	CholesterolIBA 01/2021 - 08/2014
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018 - 07/2002
4	Erythropoietin FDA Link 01/2012 - 07/2002
4	Leukemia Inhibitory FactorIBA 01/2011 - 12/2008
3	MicroRNAs (MicroRNA)IBA 01/2023 - 01/2019
3	CytokinesIBA 01/2020 - 11/2006
2	SmokeIBA 01/2022 - 01/2022
2	Cholera ToxinIBA 01/2021 - 10/2017
2	tetrandrineIBA 01/2021 - 02/2015
2	EnzymesIBA 01/2021 - 02/2008
2	ChemokinesIBA 01/2020 - 07/2008
2	LigandsIBA 11/2019 - 11/2015
2	ProteomeIBA 01/2019 - 01/2018
2	LDL CholesterolIBA 11/2017 - 10/2017
2	Rhodopsin (Visual Purple)IBA 01/2017 - 12/2006
2	Calcitonin Receptor-Like ProteinIBA 08/2015 - 01/2008
2	Protein Isoforms (Isoforms)IBA 08/2014 - 12/2007
2	Aryldialkylphosphatase (Paraoxonase)IBA 10/2013 - 02/2008
2	DNA (Deoxyribonucleic Acid)IBA 04/2010 - 07/2008
2	Neuroprotective AgentsIBA 06/2009 - 01/2006
2	Glial Fibrillary Acidic ProteinIBA 08/2008 - 04/2008
2	AdrenomedullinIBA 02/2008 - 01/2008
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 07/2002 - 03/2002
1	Cadherins (E-Cadherin)IBA 12/2023
1	TOR Serine-Threonine KinasesIBA 01/2023
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2023
1	Phenobarbital (Luminal)FDA Link 01/2023
1	IronIBA 12/2022
1	CalciumIBA 12/2022
1	RNA (Ribonucleic Acid)IBA 12/2022
1	GSK-J4IBA 07/2022
1	Histone DemethylasesIBA 07/2022
1	Histones (Histone)IBA 07/2022
1	Glycoproteins (Glycoprotein)IBA 01/2022
1	glycerylphosphoinositolIBA 01/2022
1	Lysergic Acid Diethylamide (LSD)IBA 01/2022
1	Matrix Metalloproteinase 12IBA 01/2022
1	Pancreatic Elastase (Elastase)IBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 01/2022

Therapy/Procedure

11	Therapeutics 01/2023 - 06/2007
2	Lasers (Laser) 01/2021 - 12/2009
2	Immunotherapy 01/2020 - 07/2008
1	Intravitreal Injections 10/2023